A blood RNA transcript signature for TB exposure in household contacts

BACKGROUND: Current tools for diagnosing latent TB infection (LTBI) detect immunological memory of past exposure but are unable to determine whether exposure is recent. We sought to identify a whole-blood transcriptome signature of recent TB exposure. METHODS: We studied household contacts of TB pat...

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Détails bibliographiques
Publié dans:BMC Infect Dis
Auteurs principaux: Kwan, Philip Kam Weng, Periaswamy, Balamurugan, De Sessions, Paola Florez, Lin, Wenwei, Molton, James S., Naftalin, Claire M., Naim, Ahmad Nazri Mohamed, Hibberd, Martin L., Paton, Nicholas I.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2020
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7282166/
https://ncbi.nlm.nih.gov/pubmed/32517725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12879-020-05116-1
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