Combination of Withaferin-A and CAPE Provides Superior Anticancer Potency: Bioinformatics and Experimental Evidence to Their Molecular Targets and Mechanism of Action

We have earlier reported anticancer activity in Withaferin A (Wi-A), a withanolide derived from Ashwagandha (Withania somnifera) and caffeic acid phenethyl ester (CAPE), an active compound from New Zealand honeybee propolis. Whereas Wi-A was cytotoxic to both cancer and normal cells, CAPE has been s...

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Bibliografske podrobnosti
izdano v:Cancers (Basel)
Main Authors: Sari, Anissa Nofita, Bhargava, Priyanshu, Dhanjal, Jaspreet Kaur, Putri, Jayarani F., Radhakrishnan, Navaneethan, Shefrin, Seyad, Ishida, Yoshiyuki, Terao, Keiji, Sundar, Durai, Kaul, Sunil C., Wadhwa, Renu
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7281427/
https://ncbi.nlm.nih.gov/pubmed/32380701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12051160
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