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FAK Inhibition Induces Glioblastoma Cell Senescence-Like State through p62 and p27
Focal adhesion kinase (FAK) is a central component of focal adhesions that regulate cancer cell proliferation and migration. Here, we studied the effects of FAK inhibition in glioblastoma (GBM), a fast growing brain tumor that has a poor prognosis. Treating GBM cells with the FAK inhibitor PF-573228...
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| Publicado no: | Cancers (Basel) |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7281094/ https://ncbi.nlm.nih.gov/pubmed/32349327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12051086 |
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