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Structural modeling of 2019-novel coronavirus (nCoV) spike protein reveals a proteolytically-sensitive activation loop as a distinguishing feature compared to SARS-CoV and related SARS-like coronaviruses

The 2019 novel coronavirus (2019-nCoV) is currently causing a widespread outbreak centered on Hubei province, China and is a major public health concern. Taxonomically 2019-nCoV is closely related to SARS-CoV and SARS-related bat coronaviruses, and it appears to share a common receptor with SARS-CoV...

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Publicado no:ArXiv
Main Authors: Jaimes, Javier A., Andre, Nicole M., Millet, Jean K., Whittaker, Gary R.
Formato: Artigo
Idioma:Inglês
Publicado em: Cornell University 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7280880/
https://ncbi.nlm.nih.gov/pubmed/32550245
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