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Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand Receptor Deficiency Promotes the Ductular Reaction, Macrophage Accumulation, and Hepatic Fibrosis in the Abcb4(−/−) Mouse

The tumor necrosis factor–related apoptosis-inducing ligand (TRAIL; TNFSF10) receptor (TR) is a pro-apoptotic receptor whose contribution to chronic cholestatic liver disease is unclear. Herein, we examined TRAIL receptor signaling in a mouse model of cholestatic liver injury. TRAIL receptor-deficie...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Am J Pathol
Päätekijät: Krishnan, Anuradha, Katsumi, Tomohiro, Guicciardi, Maria E., Azad, Adiba I., Ozturk, Nazli B., Trussoni, Christy E., Gores, Gregory J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Investigative Pathology 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7280758/
https://ncbi.nlm.nih.gov/pubmed/32240619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2020.02.013
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