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Complement Membrane Attack Complex: New Roles, Mechanisms of Action, and Therapeutic Targets
The complement membrane attack complex (MAC) is classically known as a cytolytic effector of innate and adaptive immunity that forms pores in the plasma membrane of pathogens or targeted cells, leading to osmolysis. Nucleated cells resist MAC-mediated cytolysis by expression of inhibitors that block...
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| I publikationen: | Am J Pathol |
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| Huvudupphovsmän: | , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Investigative Pathology
2020
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7280757/ https://ncbi.nlm.nih.gov/pubmed/32194049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2020.02.006 |
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