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Structure and dynamics of the ASB9 CUL-RING E3 Ligase
The Cullin 5 (CUL5) Ring E3 ligase uses adaptors Elongins B and C (ELOB/C) to bind different SOCS-box-containing substrate receptors, determining the substrate specificity of the ligase. The 18-member ankyrin and SOCS box (ASB) family is the largest substrate receptor family. Here we report cryo-EM...
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| Published in: | Nat Commun |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group UK
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7280518/ https://ncbi.nlm.nih.gov/pubmed/32513959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16499-9 |
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