Mechanism of effector capture and delivery by the type IV secretion system from Legionella pneumophila

Legionella pneumophila is a bacterial pathogen that utilises a Type IV secretion (T4S) system to inject effector proteins into human macrophages. Essential to the recruitment and delivery of effectors to the T4S machinery is the membrane-embedded T4 coupling complex (T4CC). Here, we purify an intact...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Meir, Amit, Macé, Kevin, Lukoyanova, Natalya, Chetrit, David, Hospenthal, Manuela K., Redzej, Adam, Roy, Craig, Waksman, Gabriel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7280309/
https://ncbi.nlm.nih.gov/pubmed/32513920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16681-z
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