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Legionella DotM structure reveals a role in effector recruiting to the Type 4B secretion system

Legionella pneumophila, a causative agent of pneumonia, utilizes the Type 4B secretion (T4BS) system to translocate over 300 effectors into the host cell during infection. T4BS systems are encoded by a large gene cluster termed dot/icm, three components of which, DotL, DotM, and DotN, form the “coup...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Meir, Amit, Chetrit, David, Liu, Luying, Roy, Craig R., Waksman, Gabriel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5802825/
https://ncbi.nlm.nih.gov/pubmed/29410427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02578-x
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