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Inflammasome activation and regulation: toward a better understanding of complex mechanisms

Inflammasomes are cytoplasmic multiprotein complexes comprising a sensor protein, inflammatory caspases, and in some but not all cases an adapter protein connecting the two. They can be activated by a repertoire of endogenous and exogenous stimuli, leading to enzymatic activation of canonical caspas...

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Detalhes bibliográficos
Publicado no:Cell Discov
Main Authors: Zheng, Danping, Liwinski, Timur, Elinav, Eran
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Singapore 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7280307/
https://ncbi.nlm.nih.gov/pubmed/32550001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41421-020-0167-x
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