FMRP promotes RNA localization to neuronal projections through interactions between its RGG domain and G-quadruplex RNA sequences

The sorting of RNA molecules to subcellular locations facilitates the activity of spatially restricted processes. We have analyzed subcellular transcriptomes of FMRP-null mouse neuronal cells to identify transcripts that depend on FMRP for efficient transport to neurites. We found that these transcr...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Goering, Raeann, Hudish, Laura I, Guzman, Bryan B, Raj, Nisha, Bassell, Gary J, Russ, Holger A, Dominguez, Daniel, Taliaferro, J Matthew
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Chromosomes and Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7279889/
https://ncbi.nlm.nih.gov/pubmed/32510328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.52621
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