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Association of Genetic Polymorphisms With Afatinib-induced Diarrhoea

Background/Aim: Afatinib, a 2(nd) generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) used in treatment of non-small cell lung cancer (NSCLC), causes diarrhoea in over 90% of patients. The association of genetic background with diarrhoea is poorly understood. Patients an...

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Bibliographic Details
Published in:In Vivo
Main Authors: SOGAWA, RINTARO, NAKASHIMA, CHIHO, NAKAMURA, TOMOMI, TAKEUCHI, KOJI, KIMURA, SAKIKO, KOMIYA, KAZUTOSHI, NARISAWA, YUTAKA, KIMURA, SHINYA, SUEOKA-ARAGANE, NAOKO
Format: Artigo
Language:Inglês
Published: International Institute of Anticancer Research 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7279839/
https://ncbi.nlm.nih.gov/pubmed/32354939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/invivo.11922
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