Automated DNA extraction using cellulose magnetic beads can improve EGFR point mutation detection with liquid biopsy by efficiently recovering short and long DNA fragments

The clinical utility of plasma DNA for detecting cancer-specific mutations has rapidly achieved recognition, but reliability has not been established because of relatively low mutation-detection rates compared with those from tissue re-biopsy. To address this shortcoming we examined efficiency, in t...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Nakashima, Chiho, Sato, Akemi, Abe, Tomonori, Kato, Junichi, Hirai, Mitsuharu, Nakamura, Tomomi, Komiya, Kazutoshi, Sueoka, Eisaburo, Kimura, Shinya, Sueoka-Aragane, Naoko
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2018
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5982773/
https://ncbi.nlm.nih.gov/pubmed/29861862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25388
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