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COPD-Related Modification to the Airway Epithelium Permits Intracellular Residence of Nontypeable Haemophilus influenzae and May Be Potentiated by Macrolide Arrest of Autophagy
INTRODUCTION: COPD is an inflammatory airway pathology associated with recurrent infection by nontypeable Haemophilus influenzae (NTHi) that is not effectively managed by macrolide antibiotic therapy. We hypothesised that NTHi is able to reside intracellularly within COPD-derived airway epithelial c...
Shranjeno v:
| izdano v: | Int J Chron Obstruct Pulmon Dis |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Dove
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7279738/ https://ncbi.nlm.nih.gov/pubmed/32581530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S245819 |
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