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COPD-Related Modification to the Airway Epithelium Permits Intracellular Residence of Nontypeable Haemophilus influenzae and May Be Potentiated by Macrolide Arrest of Autophagy

INTRODUCTION: COPD is an inflammatory airway pathology associated with recurrent infection by nontypeable Haemophilus influenzae (NTHi) that is not effectively managed by macrolide antibiotic therapy. We hypothesised that NTHi is able to reside intracellularly within COPD-derived airway epithelial c...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Int J Chron Obstruct Pulmon Dis
Κύριοι συγγραφείς: Poh, Wee-Peng, Kicic, Anthony, Lester, Susan E, Nguyen, Phan T, Bakaletz, Lauren O, Reynolds, Paul N, Hodge, Sandra, Roscioli, Eugene
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Dove 2020
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7279738/
https://ncbi.nlm.nih.gov/pubmed/32581530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S245819
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