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Comparative effectiveness of 4 natural and chemical activators of Nrf2 on inflammation, oxidative stress, macrophage polarization, and bactericidal activity in an in vitro macrophage infection model

Inflammation plays a crucial role in the defense response of the innate immune system against pathogen infection. In this study, we selected 4 compounds for their potential or proven anti-inflammatory and/or anti-microbial properties to test on our in vitro model of bacteria-infected THP-1-derived m...

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Detalles Bibliográficos
Publicado en:PLoS One
Autores principales: Ali, Malika, Bonay, Marcel, Vanhee, Valentin, Vinit, Stéphane, Deramaudt, Therese B.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7279588/
https://ncbi.nlm.nih.gov/pubmed/32511271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0234484
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