Increased extracellular vesicles mediate inflammatory signalling in cystic fibrosis

RATIONALE: Mutations in the cystic fibrosis transmembrane regulator (CFTR) gene form the basis of cystic fibrosis (CF). There remains an important knowledge gap in CF as to how diminished CFTR activity leads to the dominant inflammatory response within CF airways. OBJECTIVES: To investigate if extra...

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Publicado en:Thorax
Autores principales: Useckaite, Zivile, Ward, Mark P, Trappe, Anne, Reilly, Rebecca, Lennon, Jenny, Davage, Holly, Matallanas, David, Cassidy, Hilary, Dillon, Eugene T, Brennan, Kiva, Doyle, Sarah L, Carter, Suzanne, Donnelly, Seamas, Linnane, Barry, McKone, Edward F, McNally, Paul, Coppinger, Judith A
Formato: Artigo
Lenguaje:Inglês
Publicado: BMJ Publishing Group 2020
Materias:
Cystic Fibrosis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7279202/
https://ncbi.nlm.nih.gov/pubmed/32265339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thoraxjnl-2019-214027
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