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CX3CR1-Targeted PLGA Nanoparticles Reduce Microglia Activation and Pain Behavior in Rats with Spinal Nerve Ligation

Activation of CX3CR1 in microglia plays an important role in the development of neuropathic pain. Here, we investigated whether neuropathic pain could be attenuated in spinal nerve ligation (SNL)-induced rats by reducing microglial activation through the use of poly(D,L-lactic-co-glycolic acid) (PLG...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Noh, Chan, Shin, Hyo Jung, Lee, Seounghun, Kim, Song I, Kim, Yoon-Hee, Lee, Won Hyung, Kim, Dong Woon, Lee, Sun Yeul, Ko, Young Kwon
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7279022/
https://ncbi.nlm.nih.gov/pubmed/32423102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21103469
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