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CX3CR1-Targeted PLGA Nanoparticles Reduce Microglia Activation and Pain Behavior in Rats with Spinal Nerve Ligation

Activation of CX3CR1 in microglia plays an important role in the development of neuropathic pain. Here, we investigated whether neuropathic pain could be attenuated in spinal nerve ligation (SNL)-induced rats by reducing microglial activation through the use of poly(D,L-lactic-co-glycolic acid) (PLG...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Noh, Chan, Shin, Hyo Jung, Lee, Seounghun, Kim, Song I, Kim, Yoon-Hee, Lee, Won Hyung, Kim, Dong Woon, Lee, Sun Yeul, Ko, Young Kwon
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7279022/
https://ncbi.nlm.nih.gov/pubmed/32423102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21103469
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