Concentration and Duration of Indoxyl Sulfate Exposure Affects Osteoclastogenesis by Regulating NFATc1 via Aryl Hydrocarbon Receptor

Indoxyl sulfate (IS) is a chronic kidney disease (CKD)-specific renal osteodystrophy metabolite that affects the nuclear factor of activated T-cells, cytoplasmic 1 (NFATc1), a transcription factor promoting osteoclastogenesis. However, the mechanisms underlying the regulation of NFATc1 by IS remain...

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Bibliografski detalji
Izdano u:Int J Mol Sci
Glavni autori: Liu, Wen-Chih, Shyu, Jia-Fwu, Lim, Paik Seong, Fang, Te-Chao, Lu, Chien-Lin, Zheng, Cai-Mei, Hou, Yi-Chou, Wu, Chia-Chao, Lin, Yuh-Feng, Lu, Kuo-Cheng
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7278944/
https://ncbi.nlm.nih.gov/pubmed/32429048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21103486
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