Myostatin Inhibits Vascular Smooth Muscle Cell Proliferation and Local 14q32 microRNA Expression, But Not Systemic Inflammation or Restenosis

Myostatin is a negative regulator of muscle cell growth and proliferation. Furthermore, myostatin directly affects the expression of 14q32 microRNAs by binding the 14q32 locus. Direct inhibition of 14q32 microRNA miR-495-3p decreased postinterventional restenosis via inhibition of both vascular smoo...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Goossens, Eveline A.C., de Vries, Margreet R., Jukema, J. Wouter, Quax, Paul H.A., Nossent, A. Yaël
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7278907/
https://ncbi.nlm.nih.gov/pubmed/32429150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21103508
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