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Sirolimus and paclitaxel provoke different vascular pathological responses after local delivery in a murine model for restenosis on underlying atherosclerotic arteries

BACKGROUND: Drug‐eluting stents (DES) have been introduced successfully in clinical practice to prevent post‐angioplasty restenosis. Nevertheless, concerns about the safety of DES still exist. OBJECTIVE: To investigate the vascular pathology and transcriptional responses to sirolimus and paclitaxel...

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Détails bibliographiques
Auteurs principaux: Pires, Nuno M M, Eefting, Daniel, de Vries, Margreet R, Quax, Paul H A, Jukema, J Wouter
Format: Artigo
Langue:Inglês
Publié: BMJ Group 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994420/
https://ncbi.nlm.nih.gov/pubmed/17449502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/hrt.2006.102244
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