Plaque Rupture Complications in Murine Atherosclerotic Vein Grafts Can Be Prevented by TIMP-1 Overexpression

The current study describes the incidence and phenotype of plaque rupture complications in murine vein grafts. Since matrix metalloproteinases (MMPs) are highly involved in atherosclerotic plaque vulnerability and plaque rupture, we hypothesized that this model can be validated by overexpression of...

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Main Authors: de Vries, Margreet R., Niessen, Hans W. M., Löwik, Clemens W. G. M., Hamming, Jaap F., Jukema, J. Wouter, Quax, Paul H. A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469549/
https://ncbi.nlm.nih.gov/pubmed/23071737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047134
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