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d-Alanine–d-alanine ligase as a model for the activation of ATP-grasp enzymes by monovalent cations

The ATP-grasp superfamily of enzymes shares an atypical nucleotide-binding site known as the ATP-grasp fold. These enzymes are involved in many biological pathways in all domains of life. One ATP-grasp enzyme, d-alanine–d-alanine ligase (Ddl), catalyzes ATP-dependent formation of the d-alanyl–d-alan...

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Publié dans:J Biol Chem
Auteurs principaux: Pederick, Jordan L., Thompson, Andrew P., Bell, Stephen G., Bruning, John B.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7278361/
https://ncbi.nlm.nih.gov/pubmed/32335509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.012936
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