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Hypoxia-challenged MSC-derived exosomes deliver miR-210 to attenuate post-infarction cardiac apoptosis

BACKGROUND: Myocardial infarction (MI) is a major cause of death worldwide. Although percutaneous coronary intervention and coronary artery bypass grafting can prolong life, cardiac damage persists. In particular, cardiomyocytes have no regenerative capacity. Mesenchymal stem cells (MSCs) are attrac...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Cheng, Hao, Chang, Shufu, Xu, Rende, Chen, Lu, Song, Xiaoyue, Wu, Jian, Qian, Juying, Zou, Yunzeng, Ma, Jianying
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7278138/
https://ncbi.nlm.nih.gov/pubmed/32513270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01737-0
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