Mammalian diaphanous-related formin 1 (mDia1) coordinates mast cell migration and secretion through its actin-nucleating activity

BACKGROUND: Actin remodeling is a key regulator of mast cell (MC) migration and secretion. However, the precise mechanism underlying the coordination of these processes has remained obscure. OBJECTIVE: We sought to characterize the actin rearrangements that occur during MC secretion or chemotactic m...

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Publicat a:J Allergy Clin Immunol
Autors principals: Klein, Ofir, Krier-Burris, Rebecca A., Lazki-Hagenbach, Pia, Gorzalczany, Yaara, Mei, Yang, Ji, Peng, Bochner, Bruce S., Sagi-Eisenberg, Ronit
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7278082/
https://ncbi.nlm.nih.gov/pubmed/31279009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2019.06.028
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