Anti-Vimentin Antibodies: A Unique Antibody Class Associated with Therapy-Resistant Lupus Nephritis

BACKGROUND: Tubulointerstitial inflammation (TII) in lupus nephritis (LN) is associated with a worse prognosis. Vimentin, a filamental antigen, is commonly targeted by in situ activated B-cells in TII. The prognostic importance of high serum anti-vimentin antibodies (AVAs) in LN and their relationsh...

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Publicat a:Lupus
Autors principals: Kinloch, Andrew J., Cascino, Matthew D., Dai, Jian, Bermea, Rene S, Ko, Kichul, Vesselits, Margaret, Dragone, Leonard L, Vaknin, Nirit Mor, Legendre, Maureen, Markovitz, David M, Okoreeh, Michael K, Townsend, Michael J., Clark, Marcus R.
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7278023/
https://ncbi.nlm.nih.gov/pubmed/32216516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0961203320913606
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