How Can Biomolecules Improve Mucoadhesion of Oral Insulin? A Comprehensive Insight using Ex-Vivo, In Silico, and In Vivo Models

Currently, insulin can only be administered through the subcutaneous route. Due to the flaws associated with this route, it is of interest to orally deliver this drug. However, insulin delivered orally has several barriers to overcome as it is degraded by the stomach’s low pH, enzymatic content, and...

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Detaylı Bibliyografya
Yayımlandı:Biomolecules
Asıl Yazarlar: Amaral, Mariana, Martins, Ana Sofia, Catarino, José, Faísca, Pedro, Kumar, Pradeep, Pinto, João F., Pinto, Rui, Correia, Isabel, Ascensão, Lia, Afonso, Ricardo A., Gaspar, M. Manuela, Charmier, Adília J., Figueiredo, Isabel Vitória, Reis, Catarina Pinto
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7277740/
https://ncbi.nlm.nih.gov/pubmed/32349416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10050675
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