D-Loop Mutation G42A/G46A Decreases Actin Dynamics

Depolymerization and polymerization of the actin filament are indispensable in eukaryotes. The DNase I binding loop (D-loop), which forms part of the interface between the subunits in the actin filament, is an intrinsically disordered loop with a large degree of conformational freedom. Introduction...

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Pubblicato in:Biomolecules
Autori principali: Matsuzaki, Mizuki, Fujiwara, Ikuko, Kashima, Sae, Matsumoto, Tomoharu, Oda, Toshiro, Hayashi, Masahito, Maeda, Kayo, Takiguchi, Kingo, Maéda, Yuichiro, Narita, Akihiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7277580/
https://ncbi.nlm.nih.gov/pubmed/32397190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10050736
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