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Structural basis for the slow dynamics of the actin filament pointed end

The actin filament has clear polarity where one end, the pointed end, has a much slower polymerization and depolymerization rate than the other end, the barbed end. This intrinsic difference of the ends significantly affects all actin dynamics in the cell, which has central roles in a wide spectrum...

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Bibliografiske detaljer
Main Authors: Narita, Akihiro, Oda, Toshiro, Maéda, Yuichiro
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094112/
https://ncbi.nlm.nih.gov/pubmed/21378753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.48
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