内质网应激介导的Kupffer细胞源性TNF-α经TNFR/caspase 8途径诱导肝星状细胞凋亡

OBJECTIVE: To investigate the role of endoplasmic reticulum (ER)-stress of Kupffer cells (KCs) and KCs-derived tumor necrosis factor-α (TNF-α) in medicating apoptosis of hepatic stellate cell (HSC). METHODS: Sixty male SD rats were randomized into control group, model group, ER- stress group, deplet...

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Bibliografiske detaljer
Udgivet i:Nan Fang Yi Ke Da Xue Xue Bao
Format: Artigo
Sprog:Inglês
Udgivet: 南方医科大学学报编辑部 2020
Fag:
基础研究
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7277312/
https://ncbi.nlm.nih.gov/pubmed/32897203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12122/j.issn.1673-4254.2020.05.04
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