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内质网应激介导的Kupffer细胞源性TNF-α经TNFR/caspase 8途径诱导肝星状细胞凋亡
OBJECTIVE: To investigate the role of endoplasmic reticulum (ER)-stress of Kupffer cells (KCs) and KCs-derived tumor necrosis factor-α (TNF-α) in medicating apoptosis of hepatic stellate cell (HSC). METHODS: Sixty male SD rats were randomized into control group, model group, ER- stress group, deplet...
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| Published in: | Nan Fang Yi Ke Da Xue Xue Bao |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
南方医科大学学报编辑部
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7277312/ https://ncbi.nlm.nih.gov/pubmed/32897203 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12122/j.issn.1673-4254.2020.05.04 |
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