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Impact of Pus1 Pseudouridine Synthase on Specific Decoding Events in Saccharomyces cerevisiae
Pus1-dependent pseudouridylation occurs in many tRNAs and at multiple positions, yet the functional impact of this modification is incompletely understood. We analyzed the consequences of PUS1 deletion on the essential decoding of CAG (Gln) codons by tRNA(Gln)CUG in yeast. Synthetic lethality was ob...
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| Publicado no: | Biomolecules |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7277083/ https://ncbi.nlm.nih.gov/pubmed/32392804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10050729 |
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