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Evolution of Eukaryal and Archaeal Pseudouridine Synthase Pus10

In archaea, pseudouridine (Ψ) synthase Pus10 modifies uridine (U) to Ψ at positions 54 and 55 of tRNA. In contrast, Pus10 is not found in bacteria, where modifications at those two positions are carried out by TrmA (U54 to m(5)U54) and TruB (U55 to Ψ55). Many eukaryotes have an apparent redundancy;...

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Bibliografiske detaljer
Udgivet i:J Mol Evol
Main Authors: Fitzek, Elisabeth, Joardar, Archi, Gupta, Ramesh, Geisler, Matt
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5863725/
https://ncbi.nlm.nih.gov/pubmed/29349599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00239-018-9827-y
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