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Evolution of Eukaryal and Archaeal Pseudouridine Synthase Pus10

In archaea, pseudouridine (Ψ) synthase Pus10 modifies uridine (U) to Ψ at positions 54 and 55 of tRNA. In contrast, Pus10 is not found in bacteria, where modifications at those two positions are carried out by TrmA (U54 to m(5)U54) and TruB (U55 to Ψ55). Many eukaryotes have an apparent redundancy;...

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Bibliographic Details
Published in:J Mol Evol
Main Authors: Fitzek, Elisabeth, Joardar, Archi, Gupta, Ramesh, Geisler, Matt
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5863725/
https://ncbi.nlm.nih.gov/pubmed/29349599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00239-018-9827-y
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