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Amikacin pharmacokinetic/pharmacodynamic in intensive care unit: a prospective database
BACKGROUND: Aminoglycosides have a concentration-dependent therapeutic effect when peak serum concentration (C(max)) reaches eight to tenfold the minimal inhibitory concentration (MIC). With an amikacin MIC of 8 mg/L, the C(max) should be 64–80 mg/L. This objective is based on clinical breakpoints a...
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| Publicado no: | Ann Intensive Care |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer International Publishing
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7276966/ https://ncbi.nlm.nih.gov/pubmed/32514769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13613-020-00685-5 |
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