Salinomycin and Sulforaphane Exerted Synergistic Antiproliferative and Proapoptotic Effects on Colorectal Cancer Cells by Inhibiting the PI3K/Akt Signaling Pathway in vitro and in vivo

BACKGROUND: Both salinomycin (SAL) and sulforaphane (SFN) exert their antitumorigenic effects in various types of cancer We investigated whether combining salinomycin (SAL, an antibiotic ionophore) with sulforaphane (SFN, a phytochemical) exerted synergistic antiproliferative and proapoptotic activi...

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Vydáno v:Onco Targets Ther
Hlavní autoři: Liu, Fang, Lv, Rong-Bin, Liu, Yan, Hao, Qian, Liu, Shu-Jie, Zheng, Yuan-Yuan, Li, Cui, Zhu, Cheng, Wang, Min
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove 2020
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Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7276212/
https://ncbi.nlm.nih.gov/pubmed/32581555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S246706
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