Reduced Expression of the PP2A Methylesterase, PME-1, or the PP2A Methyltransferase, LCMT-1, Alters Sensitivity to Beta-Amyloid-Induced Cognitive and Electrophysiological Impairments in Mice

Beta-amyloid (Aβ) is thought to play a critical role in Alzheimer's disease (AD), and application of soluble oligomeric forms of Aβ produces AD-like impairments in cognition and synaptic plasticity in experimental systems. We found previously that transgenic overexpression of the PP2A methylest...

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Xehetasun bibliografikoak
Argitaratua izan da:J Neurosci
Egile Nagusiak: Staniszewski, Agnieszka, Zhang, Hong, Asam, Kesava, Pitstick, Rose, Kavanaugh, Michael P., Arancio, Ottavio, Nicholls, Russell E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Society for Neuroscience 2020
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7275859/
https://ncbi.nlm.nih.gov/pubmed/32341098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2983-19.2020
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