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The Effects of WW2/WW3 Domains of Smurf2 Molecule on CD4(+)CD25(+)/CD4(+) Proportion in Spleen of 4T1 Tumor Bearing BALB/c Mice
BACKGROUND: TGF-β has long been considered as the main inducer of Tregs in tumor microenvironment and is the reason for the aberrant number of Tregs in tumor-bearing individuals. Recently, it has been suggested that the enzyme arginase I is able to mediate the induction of Tregs in a TGF-β-independe...
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| Опубликовано в: : | Iran Biomed J |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Pasteur Institute of Iran
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7275819/ https://ncbi.nlm.nih.gov/pubmed/32306719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.29252/ibj.24.4.214 |
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