Tibetan PHD2, an allele with loss-of-function properties

Tibetans have adapted to the chronic hypoxia of high altitude and display a distinctive suite of physiologic adaptations, including augmented hypoxic ventilatory response and resistance to pulmonary hypertension. Genome-wide studies have consistently identified compelling genetic signatures of natur...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Song, Daisheng, Navalsky, Bradleigh E., Guan, Wei, Ingersoll, Cassandra, Wang, Tao, Loro, Emanuele, Eeles, Lydia, Matchett, Kyle B., Percy, Melanie J., Walsby-Tickle, John, McCullagh, James S. O., Medina, Reinhold J., Khurana, Tejvir S., Bigham, Abigail W., Lappin, Terence R., Lee, Frank S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7275716/
https://ncbi.nlm.nih.gov/pubmed/32414920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1920546117
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