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The initial engraftment of tumor cells is critical for the future growth pattern: a mathematical study based on simulations and animal experiments

BACKGROUND: Xenograft mouse tumor models are used to study mechanisms of tumor growth and metastasis formation and to investigate the efficacy of different therapeutic interventions. After injection the engrafted cells form a local tumor nodule. Following an initial lag period of several days, the s...

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Bibliografiske detaljer
Udgivet i:BMC Cancer
Main Authors: Hoffmann, Bertin, Lange, Tobias, Labitzky, Vera, Riecken, Kristoffer, Wree, Andreas, Schumacher, Udo, Wedemann, Gero
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7275472/
https://ncbi.nlm.nih.gov/pubmed/32503458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07015-9
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