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Radiotherapy and chemotherapy change vessel tree geometry and metastatic spread in a small cell lung cancer xenograft mouse tumor model

BACKGROUND: Tumor vasculature is critical for tumor growth, formation of distant metastases and efficiency of radio- and chemotherapy treatments. However, how the vasculature itself is affected during cancer treatment regarding to the metastatic behavior has not been thoroughly investigated. Therefo...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Frenzel, Thorsten, Hoffmann, Bertin, Schmitz, Rüdiger, Bethge, Anja, Schumacher, Udo, Wedemann, Gero
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5673169/
https://ncbi.nlm.nih.gov/pubmed/29107953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187144
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