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Mutational bias and the protein code shape the evolution of splicing enhancers
Exonic splicing enhancers (ESEs) are enriched in exons relative to introns and bind splicing activators. This study considers a fundamental question of co-evolution: How did ESE motifs become enriched in exons prior to the evolution of ESE recognition? We hypothesize that the high exon to intron mot...
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| Publicat a: | Nat Commun |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7275064/ https://ncbi.nlm.nih.gov/pubmed/32504065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16673-z |
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