Randomized controlled trial of N-acetylcysteine therapy for RYR1-related myopathies

OBJECTIVE: To investigate the efficacy of N-acetylcysteine (NAC) for decreasing elevated oxidative stress and increasing physical endurance in individuals with ryanodine receptor 1-related myopathies (RYR1-RM). METHODS: In this 6-month natural history assessment (n = 37) followed by a randomized, do...

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Dades bibliogràfiques
Publicat a:Neurology
Autors principals: Todd, Joshua J., Lawal, Tokunbor A., Witherspoon, Jessica W., Chrismer, Irene C., Razaqyar, Muslima S., Punjabi, Monal, Elliott, Jeffrey S., Tounkara, Fatoumata, Kuo, Anna, Shelton, Monique O., Allen, Carolyn, Cosgrove, Mary M., Linton, Melody, Michael, Darren, Jain, Minal S., Waite, Melissa, Drinkard, Bart, Wakim, Paul G., Dowling, James J., Bönnemann, Carsten G., Emile-Backer, Magalie, Meilleur, Katherine G.
Format: Artigo
Idioma:Inglês
Publicat: Lippincott Williams & Wilkins 2020
Matèries:
Null Hypothesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7274912/
https://ncbi.nlm.nih.gov/pubmed/31941795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000008872
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