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Lysosome activity is modulated by multiple longevity pathways and is important for lifespan extension in C. elegans
Lysosomes play important roles in cellular degradation to maintain cell homeostasis. In order to understand whether and how lysosomes alter with age and contribute to lifespan regulation, we characterized multiple properties of lysosomes during the aging process in C. elegans. We uncovered age-depen...
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| Vydáno v: | eLife |
|---|---|
| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
eLife Sciences Publications, Ltd
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7274789/ https://ncbi.nlm.nih.gov/pubmed/32482227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.55745 |
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