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Lysosome activity is modulated by multiple longevity pathways and is important for lifespan extension in C. elegans

Lysosomes play important roles in cellular degradation to maintain cell homeostasis. In order to understand whether and how lysosomes alter with age and contribute to lifespan regulation, we characterized multiple properties of lysosomes during the aging process in C. elegans. We uncovered age-depen...

詳細記述

保存先:
書誌詳細
出版年:eLife
主要な著者: Sun, Yanan, Li, Meijiao, Zhao, Dongfeng, Li, Xin, Yang, Chonglin, Wang, Xiaochen
フォーマット: Artigo
言語:Inglês
出版事項: eLife Sciences Publications, Ltd 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7274789/
https://ncbi.nlm.nih.gov/pubmed/32482227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.55745
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