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Lysosome activity is modulated by multiple longevity pathways and is important for lifespan extension in C. elegans

Lysosomes play important roles in cellular degradation to maintain cell homeostasis. In order to understand whether and how lysosomes alter with age and contribute to lifespan regulation, we characterized multiple properties of lysosomes during the aging process in C. elegans. We uncovered age-depen...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Sun, Yanan, Li, Meijiao, Zhao, Dongfeng, Li, Xin, Yang, Chonglin, Wang, Xiaochen
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7274789/
https://ncbi.nlm.nih.gov/pubmed/32482227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.55745
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