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Inhibition of lysine acetyltransferases impairs tumor angiogenesis acting on both endothelial and tumor cells

BACKGROUND: Understanding the signalling pathways involved in angiogenesis, and developing anti-angiogenic drugs are one of the major focuses on cancer research. Herein, we assessed the effect of CPTH6, a lysine acetyltransferase inhibitor and anti-tumoral compound, on angiogenesis-related propertie...

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Bibliographische Detailangaben
Veröffentlicht in:J Exp Clin Cancer Res
Hauptverfasser: Di Martile, Marta, Gabellini, Chiara, Desideri, Marianna, Matraxia, Marta, Farini, Valentina, Valentini, Elisabetta, Carradori, Simone, Ercolani, Cristiana, Buglioni, Simonetta, Secci, Daniela, Andreazzoli, Massimiliano, Del Bufalo, Donatella, Trisciuoglio, Daniela
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7273677/
https://ncbi.nlm.nih.gov/pubmed/32498717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-020-01604-z
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