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Host-Induced Genome Instability Rapidly Generates Phenotypic Variation across Candida albicans Strains and Ploidy States

Candida albicans is an opportunistic fungal pathogen of humans that is typically diploid yet has a highly labile genome tolerant of large-scale perturbations including chromosomal aneuploidy and loss-of-heterozygosity events. The ability to rapidly generate genetic variation is crucial for C. albica...

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Detalhes bibliográficos
Publicado no:mSphere
Main Authors: Smith, Amanda C., Hickman, Meleah A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7273350/
https://ncbi.nlm.nih.gov/pubmed/32493724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00433-20
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