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Parasexual Ploidy Reduction Drives Population Heterogeneity Through Random and Transient Aneuploidy in Candida albicans

The opportunistic pathogen Candida albicans has a large repertoire of mechanisms to generate genetic and phenotypic diversity despite the lack of meiosis in its life cycle. Its parasexual cycle enables shifts in ploidy, which in turn facilitate recombination, aneuploidy, and homozygosis of whole chr...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Hickman, Meleah A., Paulson, Carsten, Dudley, Aimee, Berman, Judith
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4512543/
https://ncbi.nlm.nih.gov/pubmed/25991822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.178020
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