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Depletion of microRNA-451 in response to allergen exposure accentuates asthmatic inflammation by regulating Sirtuin2

The incidence of asthma has increased from 5.5% to near 8% of the population, which is a major health concern. The hallmarks of asthma include eosinophilic airway inflammation that is associated with chronic airway remodeling. Allergic airway inflammation is characterized by a complex interplay of r...

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Pubblicato in:Am J Physiol Lung Cell Mol Physiol
Autori principali: Chung, Sangwoon, Lee, Yong Gyu, Karpurapu, Manjula, Englert, Joshua A., Ballinger, Megan N., Davis, Ian C., Park, Gye Young, Christman, John W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7272736/
https://ncbi.nlm.nih.gov/pubmed/32159972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00457.2019
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