Sirtuin 2 enhances allergic asthmatic inflammation

Allergic eosinophilic asthma is a chronic condition causing airway remodeling resulting in lung dysfunction. We observed that expression of sirtuin 2 (Sirt2), a histone deacetylase, regulates the recruitment of eosinophils after sensitization and challenge with a triple antigen: dust mite, ragweed,...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Lee, Yong Gyu, Reader, Brenda F., Herman, Derrick, Streicher, Adam, Englert, Joshua A., Ziegler, Mathias, Chung, Sangwoon, Karpurapu, Manjula, Park, Gye Young, Christman, John W., Ballinger, Megan N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478424/
https://ncbi.nlm.nih.gov/pubmed/30668546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.124710
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