The neuronal (pro)renin receptor and astrocyte inflammation in the central regulation of blood pressure and blood glucose in mice fed a high-fat diet

We report here that the neuronal (pro)renin receptor (PRR), a key component of the brain renin-angiotensin system (RAS), plays a critical role in the central regulation of high-fat-diet (HFD)-induced metabolic pathophysiology. The neuronal PRR is known to mediate formation of the majority of angiote...

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Veröffentlicht in:Am J Physiol Endocrinol Metab
Hauptverfasser: Worker, Caleb J., Li, Wencheng, Feng, Cheng-yuan, Souza, Lucas A. C., Gayban, Ariana Julia B., Cooper, Silvana G., Afrin, Sanzida, Romanick, Samantha, Ferguson, Bradley S., Feng Earley, Yumei
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2020
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7272727/
https://ncbi.nlm.nih.gov/pubmed/32228320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00406.2019
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